Ginsenoside Rg2 ( Ginsenoside RG2; Prosapogenin C2 )

Catalog No. M18720 CAS No. 52286-74-5

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Product Name

Ginsenoside Rg2
Note

Research use only, not for human use.
Brief Description

Ginsenoside Rg2 is one of the major active components of ginseng, act as an NF-κB inhibitor.
Description

Ginsenoside Rg2 is found in species of Panax. It inhibits LPS-stimulated production of VCAM-1 and ICAM-1, suppresses hepatic glucose production, and improves neural performance and cognition in animal models of vascular dementia.
Synonyms

Ginsenoside RG2; Prosapogenin C2
Pathway

Metabolic Enzyme/Protease
Target

P450
Recptor

GSK-3β
Research Area

Others-Field
Indication

——

CAS Number

52286-74-5
Formula Weight

785.01
Molecular Formula

C42H72O13
Purity

98%
Solubility

DMSO : ≥ 100 mg/mL; 127.39 mM
SMILES

[C@H]1(O[C@@H]([C@H]([C@@H]([C@H]1O[C@@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)C)O)O)CO)O[C@@H]1[C@@H]2[C@@]([C@@H]3[C@]([C@]4([C@H]([C@@H](C3)O)[C@@H]([C@@](O)(CCC=C(C)C)C)CC4)C)(C1)C)(CC[C@@H](C2(C)C)O)C
Chemical Name

(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((6R,8R,9R,10R,12S,13R,14R,17S)-3,12-dihydroxy-17-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol

1. Cho YS, et al. Korean J Physiol Pharmacol. 2013 Apr;17(2):133-7.

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